The Biomolecular Simulation and Computational Chemistry Group at ICRM-CNR, headed by Dr. Giorgio Colombo, focusses on the dynamic simulation of biomolecular systems and on the investigation of molecular recognition.
The fundamental questions we are trying to answer are:
. What are the sequence and structural determinants of protein stability and functional dynamics?
. What are the fundamentals of ligand binding, allostery and protein-protein interactions?
. What makes certain proteins misfold and aggregate into toxic oligomers associated with neurodegenerative diseases?
. How can we translate this knowledge in the design of new and better candidate drugs and vaccines?
For more information about our group please contact us
the colombo lab 
